If you are referring to cam sync , then absolutely makes a difference .
a bow with the cams out of sync will skew the nock left or right down the barrel the minute it leaves the arrow retention arm . , then add a broadhead with blade's that plain in the wind and accuracy between the 2 ( fieldpoint ) go out the window .
Cam sync is more important then cam timing IMO .
The enclosed barrel on the swat will not let that skewing happen .