I'll chime in on this topic again. Everything you do resting, holding, sighting will have an effect on where the projectile hits, right down to your heartbeat. Precision shooting requires everything to be the exact same for each squeeze. So of course there will be slight differences in POI when going from one shoulder to the other with a scope. Probably not enough difference for the average person to detect though. When I was shooting verticals from right and left side using the same bow and sight adjustment, my 30 yd impact was just under 2" inches different from one side to the other with elevation still right on. I made the grip on my Bowtech Patriot symmetrical but it was either the torque difference or distance between my eyes that caused the change. I just sighted in for the primary side I was using and consciously compensated for the other.